John Tilton, MD

John “Chip” Tilton, MD, is Associate Professor of Nutrition and a member of the Center for Proteomics and Bioinformatics at CWRU. Dr. Tilton is an accomplished HIV virologist who has been developing innovative proteomic and cytometric tools to analyze HIV-host interactions, particle processing, and heterogeneity. Dr. Tilton’s HIV research focuses on the role of the viral protease in processing the viral Gag and Gag/Pol polyproteins during viral assembly, budding, and maturation. His laboratory has been on the forefront of developing technology to enable the analysis of individual viral particles using flow cytometry (‘nanoscale’ flow cytometry, NFC), which has the potential to reveal the heterogeneity of viral particles and identify viral subsets that are infectious or act as immune decoys.